BBC News:
Friday, 6 September, 2002, 14:15 GMT 15:15 UK
A test which can
measure the electrical signals in the foetal brain could one day help
doctors protect babies from damage sustained in the womb.
It is one of the first times that
the activity of the brain has been measured, and showed that foetuses
could even respond to a bright light shining through their mothers'
abdomen.
The research, carried out by
scientists at the University of Arkansas, in the US, used a technique
called magnetoencephalography (MEG).
Nerve
activity in the brain involves tiny electrical impulses, and this
technique relies on the principle that even the smallest of these
creates a magnetic field.
The device employed by the
researchers can measure miniscule fluctuations in magnetic fields
using a superconductor cooled by liquid helium.
To test the device, 10 pregnant
women with foetuses aged between 28 and 36 weeks leaned into an array
of 151 sensors around their "bumps".
A fibreoptic cable was then used to
deliver light pulses - about 11 times less intense than sunlight on a
bright day.
The mother and the foetus both
produce a strong magnetic signal because of the electrical discharges
from their respective heart beats, but scientists were able to screen
these out and look instead for signs of a response to the flashing
light.
Sleeping brains
Four out of the 10 foetuses had
measurable brain responses to the light, with reaction times better in
the more highly developed foetuses.
The scientists did not believe that
no response from the other six was a reason for concern, they may
simply have been asleep or facing in the wrong direction.
The practical benefits of this
scanning system could prevent, or at least lessen brain deficits
caused by lack of nutrients from the placenta.
A frequent cause of disability is
that the placenta - the link between the blood supply of foetus and
mother - is "starving" the baby of the nutrients essential for proper
brain development.
In some cases, this may cause the
baby to be born with a brain defect such as cerebral palsy.
If "placental starving" is
suspected, in some cases it might be better, later in pregnancy, to
deliver the baby prematurely - but premature babies face other risks,
and it is hard to judge which course of action is for the best.
A test which could determine the
level of foetal brain activity might help doctors make this decision.
Research chance
Dr Penny Gowland, from the
University of Nottingham, believes that this is the most obvious
potential benefit of the technique.
She said: "It is a fascinating area,
and very little is understood about how the foetal brain develops.
This kind of thing may help us do that.
"One day, perhaps, it may help
answer questions such as whether it is beneficial to the brain to play
Mozart to your baby in the womb - but that is a long way off and
certainly not the focus of current research."